The Carcinogenic Effects of Polycyclic Aromatic Hydrocarbons

The Carcinogenic Effects of Polycyclic Aromatic Hydrocarbons

eBook - 2005
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Polycyclic aromatic hydrocarbons (PAHs), produced by the incomplete combustion of organic matter, are a significant carcinogenic threat found in the environment. This collection of 11 papers presented by Luch (Center of Cancer Research, Massachusetts Institute of Technology) discusses major aspects of PAH-induced carcinogenesis. Topics addressed include metabolic activation and detoxification of PAHs, biomonitoring of human exposure to PAHs, macromolecular adducts as biomarkers of human exposure to PAHs, DNA damage and mutagenesis induced by PAHs, mechanisms of repair of PAH-induced DNA damage, aberrant gene expression and cell signaling/epigenetic effects induced by PAHs, indicator assays for PAH-induced genotoxicity, and tumorigenicity of PAHs, genetic susceptibility to PAH-induced carcinogenesis. Distributed in the US by World Scientific. Annotation ©2005 Book News, Inc., Portland, OR (

Publisher: London : Imperial College Press ; Hackensack, NJ ; London : Distributed by World Scientific Pub., Ă2005
ISBN: 9781281866998
Characteristics: 1 online resource (xxiii, 489 pages) : illustrations
Additional Contributors: Luch, Andreas


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